Isotopically Labeled Compounds
American Radiolabeled Chemicals Inc 3H STNDRD GLASS-1 A
Tritium Standards on Glass Slides-1 each, 0-7390
Medchemexpress LLC Paraxanthine-d6 | 117490-41-2 | >99.0% | 186.20 | C7H2D6N4O2 | 1 MG
Paraxanthine-d6 is the deuterium-labeled analogue of paraxanthine supplied as a stable isotope reference material for analytical and research use. It is intended as an internal standard for quantitative mass spectrometry and tracer studies of caffeine metabolites. The material is provided as a crystalline solid with high isotopic purity and is compatible with common organic solvents.
- Stable isotope internal standard for quantitative mass spectrometry.
- High isotopic purity (>99% deuterated forms) for accurate quantitation.
- Compatible with LC-MS and tracer studies.
- Crystalline solid, soluble in DMSO and common organic solvents.
- Molecular formula C7H2D6N4O2; molecular weight 186.20.
Medchemexpress LLC Carfilzomib-d8 | 1537187-53-3 | 98.7% | 727.96 g/mol | C40H49D8N5O7 | 500 UG
Carfilzomib-d8 is a deuterium-labeled analog of carfilzomib, an irreversible proteasome inhibitor used in research. It serves as a tracer and internal standard for quantitative analysis by NMR, GC-MS, and LC-MS, and is suitable for studies of proteasome inhibition in cell models.
- Deuterium-labeled internal standard for quantitative mass spectrometry and NMR.
- Irreversible proteasome inhibitor activity; reported IC50 ≈ 5 nM in ANBL-6 and RPMI 8226 cells.
- Molecular formula C40H49D8N5O7; molecular weight 727.96 g/mol.
- Typical purity around 98.7% (batch dependent).
- Storage: protect from light; in solvent store at -80 °C up to 6 months, -20 °C up to 1 month.
Medchemexpress LLC Olaparib (cyclopropylcarbonyl-d4) | 2143107-55-3 | 98.6% | 438.49 g·mol⁻¹ | C24H19D4FN4O3 | 10 MG
Olaparib-d4-1 is a deuterium-labeled isotopologue of Olaparib provided as a stable isotope reference standard for analytical and research use. It is designed for use as an internal standard in LC-MS/MS and quantitative assays, offering consistent labeling and documented characterization to support method development and validation.
- Deuterium-labeled internal standard for mass spectrometry and quantitative assays.
- High purity supports accurate quantitation (98.6%).
- Documented molecular formula and molecular weight for precise calculations.
- Supplied in a 10 mg vial suitable for trace-level analyses.
- Applicable to pharmacokinetic, metabolite, and method validation studies.
Medchemexpress LLC L-ornithine-d2 hydrochloride | 2483831-42-9 | 99.9% | 170.63 g·mol-1 | C5H11D2ClN2O2 | 1 MG
L-ornithine-d2 hydrochloride is the deuterium-labeled hydrochloride salt of L-ornithine supplied as a white to off-white solid for use as an isotopic standard or tracer in analytical chemistry. It is intended for quantitative applications and is provided in small, measured quantities with high chemical purity.
- Deuterium-labeled for isotopic tracing and internal standard use.
- High chemical purity suitable for quantitative analysis.
- Supplied as the hydrochloride salt in small, measured quantities for analytical workflows.
- Compatible with NMR, GC-MS, and LC-MS methods as a tracer or internal standard.
American Radiolabeled Chemicals Inc ESTRADIOL-B-D-GLU-3H 50UC
Estradiol-6,7-3H(N)-17-beta-D-glucuronide 50uCi in ethanol:water (9:1), 1 mCi/ml, S.A. 30-60 Ci/mmol, M.W. 448.5, Shipped in Dry Ice
![Revvity Health Sciences Inc Ifenprodil, [Phenyl-<sup>3</sup>H]-, 250µCi (9.25MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502810373.jpg-250.jpg)
Revvity Health Sciences Inc Ifenprodil, [Phenyl-3H]-, 250µCi (9.25MBq)
Ifenprodil, [Phenyl-3H]-, 250µCi (9.25MBq)
![Revvity Health Sciences Inc AB-MECA, [<sup>125</sup>I]-(4-Amino-3-[<sup>125</sup>I]iodobenzyl-5`-N-)-, 10µCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502810490.jpg-250.jpg)
Revvity Health Sciences Inc AB-MECA, [125I]-(4-Amino-3-[125I]iodobenzyl-5`-N-)-, 10µCi
AB-MECA, [125I]-(4-Amino-3-[125I]iodobenzyl-5`-N-)-, 10µCi
Medchemexpress LLC FTISADTSK-13C 6,15N2(TFA) | 1091.01 | 1 MG
FTISADTSK-13C6,15N2 TFA is a 13C- and 15N-labeled derivative of FTISADTSK. It serves as an endogenous stable signature peptide from Trastuzumab, monitored by selected reaction monitoring (SRM). Stable heavy isotopes, such as carbon and nitrogen, are incorporated into drug molecules primarily as tracers for quantitation during drug development. This methodology, particularly deuteration, has shown potential in influencing the pharmacokinetic and metabolic profiles of drugs.
- 13C- and 15N-labeled compound.
- Endogenous stable signature peptide.
- Monitored by selected reaction monitoring (SRM).
- Useful as a tracer for quantitation in drug development.
- Incorporation of stable heavy isotopes can affect pharmacokinetic and metabolic profiles.
American Radiolabeled Chemicals Inc FLUMAZENIL ME-3H 250UC
Flumazenil-N-methyl-3H (RO 15-1788) 250uCi, 40-60 Ci/mmol, ethanol, 1 mCi/ml, M.W. 303.29, Shipped in Dry Ice, Exclusive
Medchemexpress LLC Creatine-d5 monohydrate | 99.9% | 154.18 g/mol | C4H6D5N3O3 | 5 MG
Creatine-d5 monohydrate is a deuterium-labeled form of creatine monohydrate used as a stable-isotope internal standard and analytical reference for quantitative LC-MS/MS and tracer studies. It separates from unlabeled creatine, enabling accurate quantitation in biological, food, and analytical matrices.
- Stable-isotope labeled for use as an internal standard.
- High purity (99.93%) for reliable analytical performance.
- Suitable for LC-MS/MS quantitation and tracer studies.
- Small package sizes support method development and validation.
- Provides a clear mass shift from unlabeled analyte for peak identification.
American Radiolabeled Chemicals Inc 3H STNDRD PLASTIC-1 A
Tritium Standards on Plastic Strips-1 each, 0-7390
Medchemexpress LLC Ponesimod-d7 100mg | 100MG
Ponesimod-d7 (ACT-128800-d7) is the deuterium-labeled Ponesimod (HY-10569) Ponesimod-d7 (ACT-128800) is a potent selective and orally active agonist of S1P1 with an IC50 of 6 nM in a radioligand binding assay Ponesimod-d7 activates S1P1-mediated signal transduction with high potency (EC50 5 7 nM) Ponesimod-d7 can protect against lymphocyte-mediated tissue inflammation[1 [2 [3
Medchemexpress LLC L-ornithine-d7 hydrochloride | 2483831-57-6 | 99.9% | 175.67 g/mol | C5H6D7ClN2O2 | 10 MG
L-ornithine-d7 hydrochloride is the deuterium-labeled hydrochloride salt of L-ornithine supplied as a white to off-white solid. It is intended for use as an internal standard or tracer in quantitative analytical methods (NMR, GC-MS, LC-MS) and for metabolic studies related to the urea cycle.
- Deuterium-labeled internal standard for quantitative NMR, GC-MS, and LC-MS.
- High isotopic and chemical purity suitable for analytical applications.
- Supplied as a stable solid hydrochloride for improved handling and storage.
- Available in small preweighed quantities for trace-level assays.
- Applicable as a tracer in metabolic and urea cycle research.
Medchemexpress LLC Ponesimod-d7 | 00-00-0 | MFCD18207776 | 96.5% | 468.02 | C23H18D7ClN2O4S | 10 MG
Ponesimod-d7 is the deuterium-labeled analogue of ponesimod provided for research and analytical use. This isotopically labeled compound acts as a selective S1P1 receptor agonist and is intended primarily for use as an internal standard, tracer, or reference material in pharmacokinetic and metabolic studies. It is supplied with high isotopic enrichment and high chemical purity suitable for analytical workflows.
- Deuterium-labeled analogue for tracer and internal standard applications.
- Selective S1P1 receptor activity suitable for biological assays.
- High isotopic enrichment (d7) for clear mass spectrometry distinction.
- High chemical purity appropriate for analytical and research use.
- Supplied in small, convenient quantities for method development and analysis.